The Covid 19 Pandemic is without a doubt the pretext for this seemingly fatalistic line of thought. But there is a long tradition of enquiring about the end of everything - that spans many disciplines - philosopher Ben Ware introduces the thinking behind human extinction from Kant to Voltaire to Punk and the current pandemic. Then, Tom Hughes of the EcoHealth Alliance in Malaysia explains his work, researching how changing land use in tropical areas of the planet is resulting in more diseases crossing over into humans ‒ he and others like him have been warning about this for years.

David takes a more interpretive interlude with Portuguese theatre director Tiago Rodrigues who brainstorms the end of humanity from a performative point of view, maybe the pandemic is just a dress rehearsal? Explorer and biologist Anne Luadisoit speaking from the Democratic Republic of Congo, imagines a natural environment void of humans ‒ it's not as peaceful as you might think. We hear from the second philosopher on the show Emanuele Coccia who deciphers the tiny virus ‒ part chemical part living matter ‒ and able to bring the modern world to its knees. Consultant physician and HIV AIDS specialist Marta Boffito explains exactly how a virus attacks the human body and says that we can only make limited comparisons between the COVID 19 and AIDS viruses. Finally, theoretical astrophysicist Katie Mack is back, this time with predictions on how everything will ultimately end, far far beyond our own species.