The Tunisian genius continues to reveal the “genius loci,” in search of the balance between humanity and nature, from the south to the north of a territory endowed with strong natural and cultural regional specific cities. Design is the device harnessed to gain living places at the expense of the desert’s extreme nature in Rejim Maatoug. It seeks to reveal an ancestral practice that transforms nature’s products into works of art in Sejnene, and to bring together the last holders of traditional knowledge in architecture and craftsmanship in the sustainable village of Ken. Design also aims to update the specific architecture of the houses of Ouled el Hadef in Tozeur, and to finally transcend tradition by evoking the spirit of these places in contemporary forms at Dar Hi in Nefta.